4th Edition Global Longevity Federation

1.5 million euros for research into ageing blood stem cells Junior Professor Ani Grigoryan receives ERC Starting Grant

Blood is produced from blood stem cells in the bone marrow. When this haematopoietic system ages, people over 65 often suffer from anaemia, impaired immune responses or even leukaemia. In the MANAGE HSC study, junior professor Ani Grigoryan from the Institute of Molecular Medicine wants to investigate how the bone marrow changes with age and how this affects the ageing of human blood stem cells. The junior research group leader has been awarded a Starting Grant from the European Research Council worth one and a half million euros.Readmore

Grant to Develop Portable PET Scanner for Alzheimer’s Disease

Weill Cornell Medicine researchers have received a $6.2 million, five-year grant from the National Institute on Aging, part of the National Institutes of Health, to build a portable, high-resolution Positron Emission Tomography (PET) scanner that can detect the earliest stages of Alzheimer’s disease.Readmore

Scientists can reverse brain aging in fruit flies by preventing buildup of a common protein

A new study published in Nature Communications shows that when a common cell structural protein called filamentous actin, or F-actin, builds up in the brain, it inhibits a key process that removes unnecessary or dysfunctional components within cells, including DNA, lipids, proteins and organelles. The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline. By tweaking a few specific genes in aging fruit flies’ neurons, the researchers prevented F-actin buildup, maintained cellular recycling and extended the healthy lifespan of fruit flies by approximately 30%.Readmore

Toray and Tsukuba University Launches Special Collaborative Drug Discovery and Medical Research Project to Enhance Healthy Longevity and Patient Quality of Life

Toray Industries, Inc., announced today that it concluded a collaborative agreement (see note 1) with the University of Tsukuba on October 1. They have since launched the Special Joint Research Project on Healthy Longevity and Patient Quality of Life at a new university unit. This five-year initiative will integrate Toray’s drug discovery and medical technology with the university’s expertise, infrastructure, and network to address the challenges of an aging society by improving the quality of life for the elderly and patients with progressive diseases.Readmore

Science Announces Positive Preliminary Results For Vision Restoration In Pivotal Clinical Trial

Science Corporation, a leader in brain-computer interface (“BCI”) technology, has announced the preliminary clinical trials results for its PRIMA retinal implant. The patients in the trials had lost their central visual field, which makes them unable to read and struggle to recognize faces. The results showed that the PRIMA implant restored real form vision in these patients such that sequences of letters can be read with a clinically meaningful improvement of letter acuity.Readmore

Clinique La Prairie Launches Longevity Fund To Drive Innovation In Healthspan And Lifespan

Clinique La Prairie (CLP), global leader in longevity since 1931, announces the LONGEVITY FUND, an endeavor to identify and invest in companies that revolutionize the landscape of aging, health, and wellbeing.Readmore

AbbVie to Acquire Aliada Therapeutics, Strengthening Focus in Alzheimer's Disease and Neuroscience Pipeline

Aliada's lead compound, ALIA-1758, an anti-pyroglutamate amyloid beta antibody, is a potential best-in-class therapy for Alzheimer's disease Acquisition also allows AbbVie to utilize Aliada's novel blood-brain barrier (BBB)-crossing technology to enhance discovery and development efforts across neuroscienceReadmore

Rejuvenate Biomed, the NIHR Leicester BRC, and Wellcome Leap partner for Phase 2 Study in COPD-related sarcopenia.

The Phase 2 double-blind placebo-controlled clinical trial will evaluate the potential of RJx-01 to maintain muscle integrity in older persons with severe acute exacerbation of COPD. Rejuvenate Biomed anticipates commencing patient enrollment first half 2025.Readmore

Donations from Didier Coeurnelle enable next phase of Robust Mouse Rejuvenation research program

Longevity Escape Velocity Foundation (LEVF) today welcomes two very generous donations from long-time supporter of longevity research and activism, Didier Coeurnelle. The first donation is 200,000 euros (approximately 220,000 US dollars). The second donation, of up to another 200,000 euros, is dependent on LEVF receiving matching gifts from other donors from 1st October until the end of the month (October 31st).Readmore

Dyno Therapeutics Forms New Strategic Partnership With Roche To Advance AAV Gene Therapy Vectors For Neurological Diseases

New strategic partnership leverages the power of the Dyno platform, enabling Roche to advance next-generation AAV gene therapies across multiple targets – Dyno to receive US$50 million upfront cash with the potential to earn over US$1 billion in milestones plus royalty paymentsReadmore

Common drug shows promise in extending lifespan. Scientists say mifepristone, used in cancer and reproductive care, could pave the way for anti-aging treatments.

New research from biologists at the USC Dornsife College of Letters, Arts and Sciences reveals that mifepristone, a drug best known for its use for ending early pregnancies, might also extend lifespan. The findings could pave the way for anti-aging treatments.Readmore

Researchers identify a new molecular mechanism that could help design future therapies to treat Alzheimer’s disease

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer’s patients. The study, which has been carried out in post-mortem samples of patients and in animal models of the disease, will boost the design of future therapies to address the treatment of this dementia and other neurological disorders.Readmore

UB researchers rejuvenate brain neurons through cellular reprogramming: more neurons and more brain plasticity

A research study led by the University of Barcelona describes how brain neurons in mice can be rejuvenated through a controlled cellular reprogramming cycle that helps to recover some altered neurological properties and functions. The paper could open up new perspectives for studying neurodegenerative diseases in patients. In an innovative approach, it addresses the process of cellular rejuvenation in neurons and emphasizes the role of what are known as the Yamanaka factors, key proteins for reversing ageing that have been little studied in the nervous system.Readmore

Arda Therapeutics Secures $43M Series A Financing to Advance Targeted Cell Depletion Therapies

Arda Therapeutics, a pioneer in targeted cell depletion therapies for chronic diseases, today announced the successful completion of a $43 million Series A financing round. The round was led by existing investor Andreessen Horowitz (a16z Bio + Health), with participation from Two Sigma Ventures, RV Invest, Eli Lilly and Company, GV, Biovision Ventures, Valhalla Ventures, Indicator Ventures, Alumni Ventures, LifeLink Ventures, Mana Ventures, Gaingels and ExitFund.Readmore

Brain’s waste-clearance pathways revealed for the first time

OHSU study uses imaging in neurosurgery patients to show how brain’s glymphatic system clears waste; lifestyle measures can keep system sharpReadmore

Mayo Clinic Laboratories has developed a cutting-edge suite of Alzheimer's disease testing

Mayo Clinic Laboratories has developed a cutting-edge suite of Alzheimer's disease testing. The newest assays use blood samples, avoiding the need for lumbar punctures to obtain cerebrospinal fluid. The portfolio includes an immunoassay for p-Tau217 that was developed in-house. It also includes C2N Diagnostics’ family of Precivity™ blood tests, which aid the detection of Alzheimer's pathology in symptomatic patients aged 55 and older.Readmore

Terray Therapeutics Closes Oversubscribed $120M Series B to Advance Its Generative AI Pipeline of Small Molecule Therapeutics to the Clinic

Terray Therapeutics, a biotechnology company improving human health by transforming the speed, cost, and success rate of small molecule drug development using computation integrated with novel data at scale, today announced Series B funding of $120 million. The funding will progress internal programs into clinical trials and further enhance Terray’s integrated AI platform, tNova, which it uses to power both internal and partnered programs.Readmore

Brown researchers show how gut hormones control aging in flies and how it relates to human biology

The discovery of a gut-to-brain regulation pathway in flies calls for additional consideration on how certain medications can be used to treat obesity and diabetes in humans.Readmore

Protein shakeup: McMaster researchers’ discovery may unlock age-related illnesses

McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to overall healthier aging.Readmore

Grant Award Announcement: Study on Metabolic Mechanisms of Aging in the Heart at the University of Oxford

The Longevity Science Foundation (LSF), a nonprofit organization dedicated to funding research aimed at extending the healthy human lifespan, is proud to announce a £30,000 grant award to researchers at the University of Oxford’s Department of Physiology, Anatomy, and Genetics, within the Medical Sciences Division, for the study Metabolic Mechanisms of Ageing in the Heart - Novel Dietary Interventions for Enhancing Healthspan. The research is led by Pawel Swietach, Professor of Physiology, and co-supervised by Richard Siow, Visiting Professor in the same Department at Oxford and Director of Ageing Research at King’s College London (ARK). The Foundation’s grant, which forms a critical part of the study's overall budget, is being provided over a three-year period, beginning in 2024.Readmore

Human skin map gives 'recipe' to build skin and could help prevent scarring

For the first time, researchers have created a single cell atlas of prenatal human skin to understand how skin forms, and what goes wrong in disease. Researchers from the Wellcome Sanger Institute, Newcastle University and their collaborators used single cell sequencing and other genomics techniques to create the atlas and uncover how human skin, including hair follicles, is formed. These insights could be used to create new hair follicles in regenerative medicine and skin transplants for burn victims.Readmore

Sunbird Bio Raises Additional $14 Million to Advance Broadest Blood-Based Diagnostic Platform in Alzheimer’s Disease and Other Neurological Disorders

Financing includes new funding from leading global organizations Eli Lilly and Company and EDBI Sunbird will use additional funds to further clinical development of validated diagnostic technology across key protein biomarkers in neurological disordersReadmore

Tolerance Bio, Inc. Launches with $17.2 Million in Seed Financing to Advance Thymus-Based Therapies for Immune-Mediated Diseases

Led by industry innovator Francisco Leon, M.D., Ph.D., Tolerance Bio is developing thymus preservation, regeneration, and manipulation platforms to prevent and treat immune diseases Financing led by Columbus Venture Partners, with participation by Criteria Bio Ventures, Sessa Capital, BioAdvance, Ben Franklin Technology Partners and individual biotech investors, will advance Tolerance Bio’s therapies toward clinical trialsReadmore

UR Scientists Working to Crack Enduring Mystery of Bone Loss, Regeneration

UR Scientists Working to Crack Enduring Mystery of Bone Loss, RegenerationReadmore

Shift Bioscience raises $16M to advance cell simulation AI platform

Shift Bioscience raises $16M to advance cell simulation AI platform. Investment led by BGF, with support from existing investors F-Prime Capital, Kindred Capital, and Jonathan Milner. Seed funding will accelerate development of Shift Bioscience’s platform for identification of safe rejuvenation genes, a fundamental step forward in the development of therapeutics to treat age-related diseasesReadmore

Promising ‘first’ in Alzheimer’s drug development

For the first time, scientists have developed a drug that works on both major aggregation-promoting ‘hotspots’ of the Tau protein - addressing a critical gap in current treatments.Readmore

Stanford Medicine study hints at ways to generate new neurons in old brains

The researchers’ finding suggests the possibility of designing pharmaceutical or genetic therapies to turn on new neuron production in old or injured brains.Readmore

clock.bio Raises $5.3M Seed Funding and Decodes Genetic Atlas of Human Rejuvenation Factors

clock.bio, a healthspan biotech, today announced it has raised $5.3 million in seed funding led by LocalGlobe, with participation from BlueYard Capital, Onsight Ventures, and Dr. Jonathan Milner, the Founder of Abcam. The company has made significant progress in decoding the biology of human rejuvenation, identifying more than 100 genes that jointly constitute an "Atlas of Rejuvenation Factors."Readmore

SENS Research Foundation and Lifespan.io Announce Intent to Merge, Forming a Novel Longevity Entity

In a groundbreaking announcement set to impact the future of longevity research and outreach, two historic longevity nonprofits – SENS Research Foundation and Lifespan.io (Lifespan Extension Advocacy Foundation) – have unveiled plans to merge, upon completion of regulatory approvals.Readmore

Study probes how eating less can extend lifespan

Researchers at The Jackson Laboratory conduct pivotal study into aging and lifespan to uncover new details about how diets might make people live longer — but also their negative side effectsReadmore

Booster Therapeutics Launches to Pioneer New Class of Proteasome Activator Medicines for the Treatment of a Range of Complex Diseases

Booster Therapeutics, a biotechnology company pioneering a new class of proteasome activator medicines to treat neurodegenerative and other diseases, launched today with the support of a $15 million financing led by noted life sciences investors Apollo Health Ventures and Novo Holdings. Booster was founded by Dr. Diogo Feleciano, Prof. Dr. Darci Trader, and Apollo Health Ventures, emerging from Apollo's company creation investment strategy. The company is developing small molecule therapeutics that boost the innate activity of proteasomes to restore the body’s ability to remove a wide range of disease-causing proteins.Readmore

Have We Maxed Out on Life Expectancy Gains? Current life expectancy trends support this assertion.

A paper titled “Implausibility of radical life extension in humans in the twenty-first century” was destined to ignite controversy in the longevity community. Published in Nature Aging, it lists Jay Olshansky as its corresponding author, a renowned researcher who has been studying the populational dynamics of life expectancy for decades. We delved deeper into this study and reached several prominent community members for comments. The 20th century saw average life expectancy at birth skyrocketing. For the first several decades, it was mostly fueled by lower mortality in infancy through middle adulthood due to advances in medicine and sanitation. In the later decades, as we got better in treating age-related diseases, the growth expanded to older cohorts. At around the turn of the century, suggestions were made that this “radical life extension” of about 0.3 additional years of life expectancy per year will be sustained due to further advances in medicine [2]. Olshansky et al. claim that this is not nearly the case.Readmore

How to Live 400 Years An international research team has decoded the genome of the longest-lived known vertebrate: the Greenland shark. It is huge and has special repair capabilities.

The Greenland Shark (Somniosus microcephalus), an elusive dweller of the depths of the northern Atlantic and the Arctic Ocean, is the world’s longest-living vertebrate, with an estimated lifespan of about 400 years. An international team of scientists has mapped the Greenland Shark’s genome for the first time. “The analysis of the data suggests that improved DNA repair could play an important role in its extreme longevity,” says Professor Arne Sahm, Faculty of Biology and Biotechnology at Ruhr University Bochum, Germany, and first author of the paper, which was published on September, 11, 2024 on the bioRxiv platform. The team’s work to decode the animal’s genetic makeup will shed new light on general mechanisms enabling longevity.Readmore

Tiny MicroRNAs Win Big Nobel Prize Why are microRNAs so important? Scientists asked themselves that very question when they were discovered.

It may surprise you but when microRNAs were discovered, the scientific community shrugged. So what? it seemed to say. Here we are, in 2024, and this discovery has resulted in two of its leading figures, Victor Ambros and Gary Ruvkun, receiving the Nobel Prize in Physiology or Medicine. How can something be so important to win the top award in science yet appear to be so trivial as to earn a collective meh? The reason is that we are an egocentric species. We don’t much care about worms.Readmore

Advanced AI and Ultra Wideband caregiving solution to predict falls from Clairvoyant Networks announced as finalist in $5.8m Longitude Prize on Dementia

Austin, Texas-based Clairvoyant Networks, is using soccer Ultra Wideband sensor technology to predict and prevent falls for the dementia community. The Longitude Prize on Dementia is driving the creation of AI-based assistive technologies that can help people living with dementia maintain their independence longer. The finalists were selected by an international panel of judges, informed by people with lived experience of dementia including a North American representative from Voices of Alzheimer's.Readmore

Integrated Biosciences Raises $17 Million

Silicon Valley biotech Integrated Biosciences has raised $17.2 million in seed financing to develop therapeutics for age-related diseases. The funding round included Sutter Hill Ventures, Lifespan Vision Ventures, Root Ventures, Civilization Ventures, Illumina Ventures Labs and additional funding sources.Readmore

New Research Offers Hope for Preventing Age-Related Blindness

The researchers form University of Rochester discovered that a protein called tissue inhibitor of metalloproteinases 3 (TIMP3) is overproduced in AMD. TIMP3 inhibits the activity of enzymes called matrix metalloproteinases (MMPs), which are essential for eye health. Impaired MMP activity leads to increase in another enzyme which promotes inflammation and the formation of drusen. Readmore

Helaina Raises $45 Million in Series B Funding to Accelerate the Commercialization of Human Bioactive Proteins Starting with effera™ Human Lactoferrin

Helaina has announced a successful $45 million Series B funding round, bringing its total equity funding to $83 million, which will be used to further the development of effera Human Lactoferrin, a protein product designed to support women’s health, active nutrition and healthy aging.Readmore

RYBREVANT® (amivantamab-vmjw) plus standard of care approved in the U.S. as first and only targeted regimen to cut risk of disease progression by more than half in second-line EGFR-mutated advanced lung cancer

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Insilico Medicine reports positive Phase IIa results for ISM001-055, a novel first-in-class drug treatment for idiopathic pulmonary fibrosis (IPF) designed using generative AI

Insilico Medicine, a clinical-stage generative AI-driven drug discovery company, announced positive preliminary results from its Phase IIa clinical trial evaluating ISM001-055. ISM001-055 is a first-in-class small molecule targeting TNIK (Traf2- and Nck-interacting kinase) and was designed utilizing generative AI to treat idiopathic pulmonary fibrosis (IPF). The study met both its primary endpoint of safety and its secondary efficacy endpoints, demonstrating dose-dependent response in forced vital capacity (FVC), a critical measure of lung function in IPF patients.Readmore

Scientists uncover the underlying cause for long Covid symptoms

Scientists have discovered that the long-term symptoms and impact on health experienced by global populations of COVID-19 patients may be a result of a mutation in SARS-CoV-2, the virus that causes the disease. According to the team, the mutations occur after the virus has already infected the human body. This may help to explain the ability of the virus to cause a large variety of different symptoms described as “long COVID”, affecting different tissues in human anatomy long after the initial period of incubation and resulting illness, including the respiratory system, the cardiovascular system and even the central nervous system, and could one day even lead to specific treatments to protect and clear the virus from the brain.Readmore

Miller School Study Highlights Role of Immunometabolism in Aging

This study is the first to demonstrate that metabolic abnormalities in immune cells lead to a reduced ability to generate protective immunity.Readmore

Tulane to lead a $4 million NIH-funded center for aging research

The National Institutes of Health will award up to $4 million over five years to establish a coordinating center for research on aging. Led by the Tulane National Primate Research Center and developed in partnership with the California National Primate Research Center and Baylor College of Medicine, the coordinating center will focus on advancing aging research through studies of nonhuman primates.Readmore

Researchers Link Midlife Blood Biomarkers to Late-life Dementia Risk

A research team led by Priya Palta, PhD, MHS, an associate professor of neurology at the UNC School of Medicine, has found that certain Alzheimer’s disease and neurodegenerative blood biomarkers in midlife and late life had strong associations with late-life dementia.Readmore

Longeveron® Announces U.S. FDA Grants Fast Track Designation for Lomecel-B™ for the Treatment of Mild Alzheimer’s Disease

Longeveron Inc. (NASDAQ: LGVN), a clinical stage regenerative medicine biotechnology company developing cellular therapies for life-threatening and chronic aging-related conditions, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to Lomecel-B™ for the treatment of mild Alzheimer’s Disease. Lomecel-B™ is a proprietary, scalable, allogeneic, investigational cellular therapy being evaluated across multiple indications, including Alzheimer’s Disease (Phase 2a completed), Aging-related Frailty (Phase 2b completed) and hypoplastic left heart syndrome (HLHS) (Phase 2b ongoing).Readmore

Mayo Clinic scientists define new type of memory loss in older adults

Researchers at Mayo Clinic have established new criteria for a memory-loss syndrome in older adults that specifically impacts the brain's limbic system. It can often be mistaken for Alzheimer's disease. The good news: Limbic-predominant Amnestic Neurodegenerative Syndrome, or LANS, progresses more slowly and has a better prognosis, and is now more clearly defined for doctors working to find answers for memory loss patients.Readmore

Massive biomolecular shifts occur in our 40s and 60s, Stanford Medicine researchers find

Time marches on predictably, but biological aging is anything but constant, according to a new Stanford Medicine study.Readmore

Revealing a master controller of development and ageing

University of Queensland researchers have unlocked crucial molecular secrets of ageing in cells, potentially paving the way to improve quality of life as people age.Readmore

Scientists find “master switch” which could hold the key to longer, healthier lives.

Inhibiting IL-11 in mice extends healthy lifespan and reduces hallmarks of diseases associated with ageingReadmore

UTSW study identifies RNA molecule that regulates cellular aging

Researchers discover noncoding RNA that plays unexpected role in senescence, which is involved in aging, degenerative diseases, cancer, other conditionsReadmore

Interleukin Linked to Muscle Loss, Fat Accumulation of Aging

In a new paper appearing in Nature, the team of scientists from Duke-NUS Medical School in Singapore demonstrated in preclinical mouse studies that the protein interleukin-11 (IL11) actively promotes aging, and that giving an anti-IL11 therapy not only counteracts the deleterious effects of aging but also increases lifespan. Readmore

Nutritious diet in midlife linked to healthier aging

Eating a diet rich in fruits, vegetables, whole grains, and unsaturated fats throughout midlife may increase an individual’s odds of aging healthfully, according to a new study by researchers at Harvard T.H. Chan School of Public Health.Readmore

UQ research reveals exercise brain boost can last for years

A longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in older adults for up to 5 years. Readmore

Eli Lilly's Kisunla™ (donanemab-azbt) Approved by the FDA for the Treatment of Early Symptomatic Alzheimer's Disease

The U.S. Food and Drug Administration (FDA) approved Kisunla™ (donanemab-azbt, 350 mg/20 mL once-monthly injection for IV infusion), Eli Lilly and Company's (NYSE: LLY) Alzheimer's treatment for adults with early symptomatic Alzheimer's disease (AD), which includes people with mild cognitive impairment (MCI) as well as people with the mild dementia stage of AD, with confirmed amyloid pathology.1, 2 Once-monthly Kisunla is the first and only amyloid plaque-targeting therapy with evidence to support stopping therapy when amyloid plaques are removed, which can result in lower treatment costs and fewer infusions.3-6Readmore

Cracking the aging code: Insights into lipid changes

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered numerous age-related changes in the lipid metabolism of mice, across both organs and sexes. Among these changes was the selective accumulation, throughout the body, of certain lipids produced by gut bacteria as the mice aged. Readmore

Damage to synapses caused by Alzheimer’s disease reversed

A novel treatment has been proven to effectively treat cognitive decline in mice with Alzheimer’s disease.Readmore

“LEQEMBI®” (Lecanemab) for the Treatment of Alzheimer’s Disease Launched in China China is the Third Country to Launch LEQEMBI Following the United States and Japan

Eisai Co., Ltd. and Biogen Inc. (Nasdaq: BIIB, Corporate headquarters: Cambridge, Massachusetts, announced today that the humanized anti-soluble aggregated amyloid-beta monoclonal antibody “LEQEMBI®” has been launched in China. LEQEMBI received approval in January 2024 as a treatment of mild cognitive impairment (MCI) due to Alzheimer’s disease (AD) and mild AD dementia. China is the third country to launch LEQEMBI following the United States and Japan. Readmore

UNM Center for Memory & Aging Receives $21.7 Million NIH Grant to Fund its Alzheimer’s Disease Research Center

The University of New Mexico’s Center for Memory & Aging has received a five-year $21.7 million program grant from the National Institutes of Health (NIH) to fund its Alzheimer’s Disease Research Center (ADRC).Readmore

VUMC’s Alexander Bick receives a “healthy aging” research award

Vanderbilt’s Alexander Bick, MD, PhD, has received a Hevolution/AFAR New Investigator Award in Aging Biology and Geroscience Research from the American Federation for Aging Research (AFAR) and Hevolution Foundation.Readmore

Risk factors for faster aging in the brain revealed in new study

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable Readmore

Middle-aged brain can predict your future brain health, new review finds

The team led by University College Cork (UCC) researchers reviewed past evidence from human and animal studies to illustrate that during middle age the brain undergoes significant molecular, cellular, and structural changes, and many of these changes haveReadmore

More Schooling is Linked to Slowed Aging and Increased Longevity Two years of education translated to a 2-3 percent slower pace of aging

Participants in the Framingham Heart Study who achieved higher levels of education tended to age more slowly and went on to live longer lives as compared to those who did not achieve upward educational mobility, according to a new study by researchers at Readmore

Researchers Find More Complexity in Aging Brain’s Memory Decline

Researchers from The University of Texas at Dallas Center for Vital Longevity (CVL) have discovered that brain correlates of age-related memory decline are more complicated than previously believed, a finding that could affect efforts to preserve cognitivReadmore

Looking to rewind the aging clock

Harvard researchers create model that better measures biological age, distinguishes between harmful and adaptive changes during life Readmore

Schizophrenia and aging may share a common biological basis Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues.

Researchers from the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schiReadmore

TELOMIR PHARMACEUTICALS RELEASES NEW PRE-CLINICAL DATA FOR TELOMIR-1 TO BE PRESENTED AT THE GLOBAL LONGEVITY FEDERATION CONFERENCE IN LAS VEGAS ON MARCH 26TH

Poster presentation delivers pre-clinical results that demonstrate that its lead development product, Telomir-1, elongates telomere caps on human normal embryonic fibroblast cells Readmore

Anti-ageing drug rapamycin improves immune function through endolysosomes, Protection against an increase in pro-inflammatory factors with age

A research group at the Max Planck Institute for Biology of Ageing has discovered in fruit flies that rapamycin activates the so-called endolysosomes, which have a similar function to the stomach in our cells.Readmore

£3 million UKRI funding to support research into better health, ageing, and wellbeing

The University of Cambridge has received UKRI funding for research on age-related biological changes in model organisms as part of a national collaboration. Readmore

Damage to cell membranes causes cell aging

A new study has found that mechanical damage to the cell membrane may induce cellular senescence in human cells. Readmore

Could a Drug Prevent Hearing Loss from Loud Music and Aging?

Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss.Readmore

Keys to aging hidden in the leaves

Scientists have known about a particular organelle in plant cells for over a century. However, UC Riverside scientists have only now discovered that organelle’s key role in aging. Readmore

Life span increases in mice when specific brain cells are activated

Brain cells communicate with fat tissue to produce cellular fuel, counteract effects of agingReadmore

Brock-led research uncovers breakthrough in age-related diseases

Newman Sze, Brock University Professor of Health Sciences and Canada Research Chair in Mechanisms of Health and Disease, leads an international team that has uncovered a key link between oxidative stress, aging and chronic diseases, paving the way for posReadmore