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GlycanAge, USA [12:15PM-01:00PM]
Title: Glycans as biomarkers and functional effectors of ageing and disease
The GlycanAge test of biological age is the most actionable ageing biomarker currently available in longevity and holistic medicine space, as per the recent Cell paper published by the Biomarkers of Aging Consortium (Moqri et al.). The test measures changes in the glycome of immunoglobulin G (IgG), a key component of the immune system that plays a critical role in inflammageing and age-related diseases.
IgG glycans have a high level of granularity for several reasons. Changes in glycans have been observed in over 70 different conditions, diseases and pathologies. Secondly, glycans are powerful disease discriminators, discriminating very well between healthy and non-healthy individuals, as well as between disease that have similar clinical presentations. Thirdly, they are a powerful tool in chronic disease prediction as they change years in advance, before any symptoms are noticeable.
The GlycanAge test is backed by over 300 research studies and 20+ years of research. It is responsive to lifestyle and pharmaceutical interventions, making it a powerful tool for predicting future health and tracking the effectiveness of preventative health strategies.
Dr Lucija Sironic is a UK-trained and GMC-registered medical doctor who transitioned from working in the public healthcare sector, where she practised disease management medicine, to working in a vibrant start-up environment that translates glycoscience findings from bench to bedside. Lucija works as a neuroglycobiology researcher and product development scientist at GlycanAge, and is passionate about healthspan optimisation and improvement of disease prevention policies.